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Observe Closely (3)pentobarbital will minimize the level or effect of diazepam intranasal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Robust or average CYP3A4 inducers may well improve price of diazepam elimination; hence, efficacy of diazepam could be lessened.Pentobarbital belongs towards the barbiturate course